SNARE

Cog6 knockdown affects the steady-state distribution of Stx6-associated SNARE complex

Sima Lev Web Team Leave a Comment
Prof. Sima Lev and her student Orly Laufman: Cog6 knockdown affects the steady-state distribution of Stx6-associated SNARE complex

Prof. Sima Lev and her student Orly Laufman revealed how a membrane-tethering complex promotes the transport of vesicles from endosomes to the trans-Golgi network (TGN). The conserved oligomeric Golgi (COG) complex helps to recycle proteins back through the Golgi apparatus… Continue Reading →

SNARE complexes along the secretory and endocytic pathways in mammals

Sima Lev Web Team Leave a Comment
Slide 4: SNARE complexes along the secretory and endocytic pathways in mammals.

Schematic summary of known mammalian SNARE complexes and their sites of action along the exocytic and endocytic pathways. Potential v-SNAREs are indicated in red; the Sec1/Munc18 SM proteins for some SNARE complexes are marked in purple. Abbreviations: ER, endoplasmic reticulum;… Continue Reading →