endocytic pathways

Tethering complexes along the secretory and endocytic pathways in mammals

Sima Lev Web Team Leave a Comment
slide7: Tethering complexes along the secretory and endocytic pathways in mammals

Multisubunit tethering complexes (MTCs) interact with soluble SNAREs to couple vesicular tethering with fusion. Conserved Oligomeric Golgi (COG) and Golgi-associated retrograde protein (GARP) MTCs interact with multiple SNAREs on the Golgi membranes. The eight subunits of the COG complex are… Continue Reading →

SNARE complexes along the secretory and endocytic pathways in mammals

Sima Lev Web Team Leave a Comment
Slide 4: SNARE complexes along the secretory and endocytic pathways in mammals.

Schematic summary of known mammalian SNARE complexes and their sites of action along the exocytic and endocytic pathways. Potential v-SNAREs are indicated in red; the Sec1/Munc18 SM proteins for some SNARE complexes are marked in purple. Abbreviations: ER, endoplasmic reticulum;… Continue Reading →