Tethering complexes along the secretory and endocytic pathways in mammals

Tethering complexes along the secretory and endocytic pathways in mammals

Multisubunit tethering complexes (MTCs) interact with soluble SNAREs to couple vesicular tethering with fusion. Conserved Oligomeric Golgi (COG) and Golgi-associated retrograde protein (GARP) MTCs interact with multiple SNAREs on the Golgi membranes. The eight subunits of the COG complex are… Continue Reading