Prof. Sima Lev: VAP-B and its role in Amyotrophic lateral sclerosis
The VAPs (VAMP-associated proteins) are highly conserved integral endoplasmic reticulum (ER)-membrane proteins, implicated in diverse cellular functions, including regulation of lipid transport and homeostasis, membrane trafficking, neurotransmitter release, stabilization of presynaptic microtubules, and the unfolded protein response (UPR). A single… Continue Reading
